Random cell movement promotes synchronization of the segmentation clock
نویسندگان
چکیده
منابع مشابه
Random cell movement promotes synchronization of the segmentation clock.
In vertebrate somitogenesis, the expression of segmentation clock genes oscillates and the oscillation is synchronized over nearby cells. Both experimental and theoretical studies have shown that the synchronization among cells is realized by intercellular interaction via Delta-Notch signaling. However, the following questions emerge: (i) During somitogenesis, dynamic rearrangement of relative ...
متن کاملCollective cell movement promotes synchronization of coupled genetic oscillators.
Collective cell movement is a crucial component of embryonic development. Intercellular interactions regulate collective cell movement by allowing cells to transfer information. A key question is how collective cell movement itself influences information flow produced in tissues by intercellular interactions. Here, we study the effect of collective cell movement on the synchronization of locall...
متن کاملCell Timer/Cell Clock
Like the biological clock in the body, replication of each cell type (even different cells of the same organism) follows a timing program. Abnormal function of this timer could be an alarm for a disease like cancer. DNA replication starts from a specific point on the chromosome that is called the origin of replication. In contrast to prokaryotes in which DNA replication starts from a single ...
متن کاملClock Synchronization
When Charles V retired in weariness from the greatest throne in the world to the solitude of the monastery at Yuste, he occupied his leisure for some weeks trying to regulate two clocks. It proved very difficult. One day, it is recorded, he turned to his assistant and said: “To think that I attempted to force the reason and conscience of thousands of men into one mould, and I cannot make two cl...
متن کاملByzantine Clock Synchronization
An informal description is given of three fault-tolerant clock-synchronization algorithms. These algorithms work in the presence of arbitrary kinds of failure, including "twofaced" clocks. Two of the algorithms are derived from Byzantine Generals solutions. 1. I n t r o d u c t i o n Many multiprocess systems, especially process-control systems, require processes to maintain clocks that are syn...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2010
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0907122107